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Downregulation of type I collagen expression in the Achilles tendon by dexamethasone: a controlled laboratory study

Abstract Background Spontaneous Achilles tendon rupture associated with long-term dexamethasone (Dex) use has been reported. However, few studies have investigated the potential mechanism. The aim of this study was to evaluate the effects of oral Dex on type I collagen in humans and rats and its ass...

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Principais autores: Zilu Ge, Hong Tang, Wan Chen, Yunjiao Wang, Chengsong Yuan, Xu Tao, Binghua Zhou, Kanglai Tang
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2020-02-01
coleção:Journal of Orthopaedic Surgery and Research
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Acesso em linha:http://link.springer.com/article/10.1186/s13018-020-01602-z
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