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An Overview of the Stability and Delivery Challenges of Commercial Nucleic Acid Therapeutics

Nucleic acid (NA)-based biopharmaceuticals have emerged as promising therapeutic modalities. NA therapeutics are a diverse class of RNA and DNA and include antisense oligonucleotides, siRNA, miRNA, mRNA, small activating RNA, and gene therapies. Meanwhile, NA therapeutics have posed significant stab...

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Autores principales: Rahul G. Ingle, Wei-Jie Fang
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI AG 2023-04-01
Colección:Pharmaceutics
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Acceso en línea:https://www.mdpi.com/1999-4923/15/4/1158
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