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Immunosuppressive Effects of Myeloid-Derived Suppressor Cells in Cancer and Immunotherapy

The primary function of myeloid cells is to protect the host from infections. However, during cancer progression or states of chronic inflammation, these cells develop into myeloid-derived suppressor cells (MDSCs) that play a prominent role in suppressing anti-tumor immunity. Overcoming the suppress...

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Bibliografiske detaljer
Principais autores: Mithunah Krishnamoorthy, Lara Gerhardt, Saman Maleki Vareki
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2021-05-01
Serier:Cells
Fag:
Online adgang:https://www.mdpi.com/2073-4409/10/5/1170
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