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Detection of BRAF mutations in patients with hairy cell leukemia and related lymphoproliferative disorders

Hairy cell leukemia has been shown to be strongly associated with the BRAF V600E mutation. We screened 59 unenriched archived bone marrow aspirate and peripheral blood samples from 51 patients with hairy cell leukemia using high resolution melting analysis and confirmatory Sanger sequencing. The BRA...

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Autors principals: Piers A. Blombery, Stephen Q. Wong, Chelsee A. Hewitt, Alexander Dobrovic, Ellen L. Maxwell, Surender Juneja, George Grigoriadis, David A. Westerman
Format: Artigo
Idioma:Inglês
Publicat: Ferrata Storti Foundation 2012-05-01
Col·lecció:Haematologica
Accés en línia:https://haematologica.org/article/view/6306
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