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Structural insight into toxin secretion by contact-dependent growth inhibition transporters

Bacterial contact-dependent growth inhibition (CDI) systems use a type Vb secretion mechanism to export large CdiA toxins across the outer membrane by dedicated outer membrane transporters called CdiB. Here, we report the first crystal structures of two CdiB transporters from Acinetobacter baumannii...

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Principais autores: Jeremy Guerin, Istvan Botos, Zijian Zhang, Karl Lundquist, James C Gumbart, Susan K Buchanan
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications Ltd 2020-10-01
coleção:eLife
Assuntos:
type V secretion system
Omp85
TpsB
toxin secretion
contact dependent growth inhibition
acinetobacter baumannii
Acesso em linha:https://elifesciences.org/articles/58100
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