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MicroRNA Machinery Genes as Novel Biomarkers for Cancer

MicroRNAs (miRNAs) directly and indirectly affect tumorigenesis. To be able to perform their myriad roles, miRNA machinery genes, such as Drosha, DGCR8, Dicer1, XPO5, TRBP, and AGO2, must generate precise miRNAs. These genes have specific expression patterns, protein-binding partners, and biochemica...

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Principais autores: Jing-Tao eHuang, Jin eWang, Vibhuti eSrivastava, Subrata eSen, Song-Mei eLiu
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2014-05-01
Series:Frontiers in Oncology
Assuntos:
Cancer
miRNA
biomarker
machinery genes
alterations
Acceso en liña:http://journal.frontiersin.org/Journal/10.3389/fonc.2014.00113/full
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