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Regulation of Leukocytes by TspanC8 Tetraspanins and the “Molecular Scissor” ADAM10

A disintegrin and metalloproteinase 10 (ADAM10) is a ubiquitous transmembrane protein that functions as a “molecular scissor” to cleave the extracellular regions from its transmembrane target proteins. ADAM10 is well characterized as the ligand-dependent activator of Notch proteins, which control ce...

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Autors principals: Alexandra L. Matthews, Chek Ziu Koo, Justyna Szyroka, Neale Harrison, Aditi Kanhere, Michael G. Tomlinson
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2018-07-01
Col·lecció:Frontiers in Immunology
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Accés en línia:https://www.frontiersin.org/article/10.3389/fimmu.2018.01451/full
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