Adoptive γδ T cell therapy controls cytomegalovirus infection in preclinical transplantation models

Abstract γδ T cells show promise for anti-tumoral therapies but have yet to be evaluated to treat infectious diseases. In this preclinical study, we assess a Vδ1 + γδ T cell-based adoptive cell therapy, named Delta One T cells, to treat cytomegalovirus (CMV) infection in high-risk transplant recipie...

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Autors principals:	Gabriel Marsères, Coline Gentil, Claire Tinevez, Maxime Courant, Anaïs Cosentino, Selma Cornillot-Clément, Victor Bigot, Vincent Pitard, Atika Zouine, Julien Izotte, Isabelle Garrigue, Valérie Prouzet-Mauleon, Béatrice Turcq, Dany Anglicheau, Edouard Forcade, Hannah Kaminski, Bruno Silva-Santos, Pierre Merville, Myriam Capone, Julie Déchanet-Merville, Lionel Couzi
Format:	Artigo
Idioma:	Inglês
Publicat:	Nature Portfolio 2026-02-01
Col·lecció:	Nature Communications
Accés en línia:	https://doi.org/10.1038/s41467-026-69538-2
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