QR код

Novel peptide inhibitor of human tumor necrosis factor-α has antiarthritic activity

Abstract The inhibition of tumor necrosis factor (TNF)-α trimer formation renders it inactive for binding to its receptors, thus mitigating the vicious cycle of inflammation. We designed a peptide (PIYLGGVFQ) that simulates a sequence strand of human TNFα monomer using a series of in silico methods,...

Повний опис

Збережено в:
Автори: Debasis Sahu, Charu Gupta, Ragothaman M. Yennamalli, Shikha Sharma, Saugata Roy, Sadaf Hasan, Pawan Gupta, Vishnu Kumar Sharma, Sujit Kashyap, Santosh Kumar, Ved Prakash Dwivedi, Xiangli Zhao, Amulya Kumar Panda, Hasi Rani Das, Chuan-Ju Liu
Формат: Artigo
Мова:Inglês
Опубліковано: Nature Portfolio 2024-06-01
Серія:Scientific Reports
Предмети:
Tumor necrosis factor (TNF)α
Inflammation
Peptide
Nuclear factor kappa B (NFκB)
Collagen-induced arthritis (CIA)
Онлайн доступ:https://doi.org/10.1038/s41598-024-63790-6
Теги: Додати тег
Немає тегів, Будьте першим, хто поставить тег для цього запису!

Схожі ресурси