ZFP281-BRCA2 prevents R-loop accumulation during DNA replication
R-loops are prevalent in mammalian genomes and involved in many fundamental cellular processes. Here, Wang et al. report that ZFP281 cooperates with BRCA2 in preventing R-loop accumulation to facilitate DNA replication in embryonic stem cells.
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| Главные авторы: | , , , , , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Portfolio
2022-06-01
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| Серии: | Nature Communications |
| Online-ссылка: | https://doi.org/10.1038/s41467-022-31211-9 |
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