Extracellular vesicles secreted by 3D tumor organoids are enriched for immune regulatory signaling biomolecules compared to conventional 2D glioblastoma cell systems

BackgroundNewer 3D culturing approaches are a promising way to better mimic the in vivo tumor microenvironment and to study the interactions between the heterogeneous cell populations of glioblastoma multiforme. Like many other tumors, glioblastoma uses extracellular vesicles as an intercellular com...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Martina Schuster, Frank K. Braun, Dapi Meng-Lin Chiang, Christina Ludwig, Chen Meng, Christian Grätz, Benedikt Kirchner, Martin Proescholdt, Peter Hau, Ortrud K. Steinlein, Michael W. Pfaffl, Markus J. Riemenschneider, Marlene Reithmair
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2024-04-01
Schriftenreihe:	Frontiers in Immunology
Schlagworte:	glioblastoma multiforme brain cancer 3D organoid model extracellular vesicle EV microRNA
Online-Zugang:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1388769/full
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!