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Impact of CodY protein on metabolism, sporulation and virulence in Clostridioides difficile ribotype 027.

Toxin synthesis and endospore formation are two of the most critical factors that determine the outcome of infection by Clostridioides difficile. The two major toxins, TcdA and TcdB, are the principal factors causing damage to the host. Spores are the infectious form of C. difficile, permit survival...

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Autors principals: Nadine Daou, Yuanguo Wang, Vladimir M Levdikov, Madhumitha Nandakumar, Jonathan Livny, Laurent Bouillaut, Elena Blagova, Keshan Zhang, Boris R Belitsky, Kyu Rhee, Anthony J Wilkinson, Xingmin Sun, Abraham L Sonenshein
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2019-01-01
Col·lecció:PLoS ONE
Accés en línia:https://doi.org/10.1371/journal.pone.0206896
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