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Hallmarks of primate lentiviral immunodeficiency infection recapitulate loss of innate lymphoid cells

Innate lymphoid cells (ILCs) have been shown to be depleted during HIV-1 infection. Here the authors show that ILC loss is associated with CD4 depletion and gastrointestinal damage in a primate model of SIV infection.

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Bibliografiska uppgifter
Huvudupphov: Joseph C. Mudd, Kathleen Busman-Sahay, Sarah R. DiNapoli, Stephen Lai, Virginia Sheik, Andrea Lisco, Claire Deleage, Brian Richardson, David J. Palesch, Mirko Paiardini, Mark Cameron, Irini Sereti, R. Keith Reeves, Jacob D. Estes, Jason M. Brenchley
Materialtyp: Artigo
Språk:Inglês
Utgiven: Nature Portfolio 2018-09-01
Serie:Nature Communications
Länkar:https://doi.org/10.1038/s41467-018-05528-3
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