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HLA-A*01:01 allele diminishing in COVID-19 patients population associated with non-structural epitope abundance in CD8+ T-cell repertoire

In mid-2021, the SARS-CoV-2 Delta variant caused the third wave of the COVID-19 pandemic in several countries worldwide. The pivotal studies were aimed at studying changes in the efficiency of neutralizing antibodies to the spike protein. However, much less attention was paid to the T-cell response...

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Principais autores: Maxim Shkurnikov, Stepan Nersisyan, Darya Averinskaya, Milena Chekova, Fedor Polyakov, Aleksei Titov, Dmitriy Doroshenko, Valery Vechorko, Alexander Tonevitsky
פורמט: Artigo
שפה:Inglês
יצא לאור: PeerJ Inc. 2023-01-01
סדרה:PeerJ
נושאים:
COVID-19
MHC-I
HLA-A*01:01
T-cell immune response
ELISpot
גישה מקוונת:https://peerj.com/articles/14707.pdf
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