Protocol for a multinational risk-stratified randomised controlled trial in paediatric Crohn’s disease: methotrexate versus azathioprine or adalimumab for maintaining remission in patients at low or high risk for aggressive disease course

Introduction Immunomodulators such as thiopurines (azathioprine (AZA)/6-mercaptopurine (6MP)), methotrexate (MTX) and biologics such as adalimumab (ADA) are well established for maintenance of remission within paediatric Crohn’s disease (CD). It remains unclear, however, which maintenance medication...

Celý popis

Podrobná bibliografie

Hlavní autoři:	Sibylle Koletzko, Richard K Russell, Arie Levine, Dan Turner, Rachel E Harris, Lissy de Ridder, Frank M Ruemmele, Nicholas M Croft, Marina Aloi, Gigi Veereman, Mattias Neyt, Laetitia Bigot
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMJ Publishing Group 2020-07-01
Edice:	BMJ Open
On-line přístup:	https://bmjopen.bmj.com/content/10/7/e034892.full
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!