A Single Point Mutation in GraS Drives Co-Evolution of Vancomycin Resistance and Virulence in <i>Staphylococcus aureus</i>
The emergence of vancomycin-intermediate <i>Staphylococcus aureus</i> (VISA) threatens the efficacy of this last-line antibiotic. The GraSR two-component system is frequently mutated in VISA strains. Here, we demonstrate that the GraS(T136I) point mutation, identified in the clinical VISA isolate XN...
Gespeichert in:
| Hauptverfasser: | , , , , , , |
|---|---|
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
MDPI AG
2026-05-01
|
| Schriftenreihe: | Microorganisms |
| Schlagworte: | |
| Online-Zugang: | https://www.mdpi.com/2076-2607/14/5/1151 |
| Tags: |
Keine Tags, Fügen Sie das erste Tag hinzu!
|