Stress-induced GHS-R1a expression in medial prefrontal cortical neurons promotes vulnerability to anxiety in mice

Abstract The neural basis of anxiety is unclear, which hinders the treatment of anxiety disorders. Here, we found that αCaMKII+ neurons in the medial prefrontal cortex (mPFCαCaMKII+) responded to stressors with increased activity both under physiological conditions and after repeated restraint stres...

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Bibliografiske detaljer

Principais autores:	Liu Yang, Meng Zhang, Xiaomin Sun, Anqi Du, Jiajia Jia, Nan Li, Gonghui Hu, Yingchang Lu, Sihan Wang, Jingsai Zhang, Wenjie Chen, Hanbing Yu, Yu Zhou
Format:	Artigo
Sprog:	Inglês
Udgivet:	Nature Portfolio 2025-03-01
Serier:	Communications Biology
Online adgang:	https://doi.org/10.1038/s42003-025-07802-9
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