Association of natriuretic peptides and receptor activity with cardio-metabolic health at middle age

Abstract Natriuretic peptides (NP) have multiple actions benefitting cardiovascular and metabolic health. Although many of these are mediated by Guanylyl Cyclase (GC) receptors NPR1 and NPR2, their role and relative importance in vivo is unclear. The intracellular mediator of NPR1 and NPR2, cGMP, ci...

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Autors principals:	Timothy C. R. Prickett, Eric A. Espiner, John F. Pearson
Format:	Artigo
Idioma:	Inglês
Publicat:	Nature Portfolio 2024-04-01
Col·lecció:	Scientific Reports
Matèries:	ANP BNP CNP cGMP NPR1 Causal mediation analysis
Accés en línia:	https://doi.org/10.1038/s41598-024-60677-4
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