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Aberrant activation of bone marrow Ly6C high monocytes in diabetic mice contributes to impaired glucose tolerance.

Accumulating evidence indicates that diabetes and obesity are associated with chronic low-grade inflammation and multiple organ failure. Tissue-infiltrated inflammatory M1 macrophages are aberrantly activated in these conditions and contribute to hyperglycemia and insulin resistance. However, it is...

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Principais autores: Yosuke Ikeda, Noriyuki Sonoda, Battsetseg Bachuluun, Shinichiro Kimura, Yoshihiro Ogawa, Toyoshi Inoguchi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2020-01-01
Colecção:PLoS ONE
Acesso em linha:https://doi.org/10.1371/journal.pone.0229401
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