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Deciphering the role of ferroptosis in rheumatoid arthritis: Synovial transcriptome analysis and immune infiltration correlation

The pathogenesis of rheumatoid arthritis (RA) remains elusive. The initiation of joint degeneration is characterized by the loss of self-tolerance in peripheral joints. Ferroptosis, a form of regulated cell death, holds significant importance in the pathophysiology of inflammatory arthritis, primari...

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Principais autores: Hongli Wang, Miaomiao Zhang, Yiping Hu, Juan He, Yuchao Zhong, Yong Dai, Qingwen Wang
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2024-07-01
Serier:Heliyon
Fag:
Rheumatoid arthritis
Ferroptosis
Iron accumulation
Lipid peroxidation
Differential gene analysis
Immune cell infiltration
Online adgang:http://www.sciencedirect.com/science/article/pii/S2405844024096798
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