Characterization of the Cynomolgus Macaque Model of Marburg Virus Disease and Assessment of Timing for Therapeutic Treatment Testing

Marburg virus (MARV) causes severe disease and high mortality in humans. The objective of this study was to characterize disease manifestations and pathogenesis in cynomolgus macaques exposed to MARV. The results of this natural history study may be used to identify features of MARV disease useful i...

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Principais autores:	Elizabeth E. Zumbrun, Carly B. Garvey, Jay B. Wells, Ginger C. Lynn, Sean Van Tongeren, Jesse T. Steffens, Kelly S. Wetzel, Laura M. Gomba, Kristan A. O’Brien, Franco D. Rossi, Xiankun Zeng, Eric D. Lee, Jo Lynne W. Raymond, Diana A. Hoffman, Alexandra N. Jay, Elizabeth S. Brown, Paul A. Kallgren, Sarah L. Norris, Jean Cantey-Kiser, Humza Kudiya, Chris Arthur, Christiana Blair, Darius Babusis, Victor C. Chu, Bali Singh, Roy Bannister, Danielle P. Porter, Tomas Cihlar, John M. Dye
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2023-11-01
Colecção:	Viruses
Assuntos:	Marburg virus filovirus nonhuman primate cynomolgus macaque intramuscular animal model
Acesso em linha:	https://www.mdpi.com/1999-4915/15/12/2335
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