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Synthesis, characterization, biological screening and in silico studies of novel pyrazole-chalcone derivatives as potent aromatase inhibitors for breast cancer therapy

Abstract Background Chalcone derivatives, which are known for their non-steroidal anticancer properties, have been extensively studied. One potential application of chalcone is as aromatase inhibitors, a crucial strategy for treating estrogen receptor-positive (ER +) breast cancer. Thirteen chalcone...

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Autori principali: Ishvarchandra Parmar, Samir Patel, Umang Shah, Chirag Patel, Alkesh Patel, Arya Patel
Natura: Artigo
Lingua:Inglês
Pubblicazione: SpringerOpen 2025-11-01
Serie:Future Journal of Pharmaceutical Sciences
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Accesso online:https://doi.org/10.1186/s43094-025-00914-3
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