A Novel Series of [1,2,4]Triazolo[4,3-a]Pyridine Sulfonamides as Potential Antimalarial Agents: In Silico Studies, Synthesis and In Vitro Evaluation

For the development of new and potent antimalarial drugs, we designed the virtual library with three points of randomization of novel [1,2,4]triazolo[4,3-<i>a</i>]pyridines bearing a sulfonamide fragment. The library of 1561 compounds has been investigated by both virtual screening and molecular doc...

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主要な著者:	Veronika R. Karpina, Svitlana S. Kovalenko, Sergiy M. Kovalenko, Oleksandr G. Drushlyak, Natalya D. Bunyatyan, Victoriya A. Georgiyants, Vladimir V. Ivanov, Thierry Langer, Louis Maes
フォーマット:	Artigo
言語:	Inglês
出版事項:	MDPI AG 2020-09-01
シリーズ:	Molecules
主題:	[1,2,4]triazolo[4,3-<i>a</i>]pyridines sulfonamide <i>Plasmodium falciparum</i> antimalarial falcipain-2 virtual screening
オンライン･アクセス:	https://www.mdpi.com/1420-3049/25/19/4485
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