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Two Cysteines in Raf Kinase Inhibitor Protein Make Differential Contributions to Structural Dynamics In Vitro

As a scaffolding protein, Raf kinase binding protein (RKIP) is involved in a variety of cellular pathways, including the Raf–MEK–ERK-cascade. It acts as a negative regulator by binding to its partners, making it an attractive target in the development of therapeutic strategies for cancer. Despite it...

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Principais autores: Hyun Sang Cho, Mohammad Faysal Al Mazid, Eun-Young Lee, Md Abu Rayhan, Hyoun Sook Kim, Byung Il Lee, Hye Jin You
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2025-01-01
Serier:Molecules
Fag:
Raf kinase inhibitor protein
dimerization
cysteine
cancer
Online adgang:https://www.mdpi.com/1420-3049/30/2/384
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