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Glutathione S-transferase M1 and T1 polymorphisms and the risk of mild hepatotoxicity induced by carbamazepine in a tunisian population study

Abstract Background The aim of this study was to evaluate whether the glutathione S-transferase M1 (GSTM1) and T1 (GSTT1) null alleles may contribute to carbamazepine-induced hepatotoxicity. Methods A cross-sectional prospective study was conducted to identify the frequency distribution of GSTM1 and...

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Principais autores: Chahra Chbili, Anis Hassine, Neila Fathallah, Manel Nouira, Salma Naija, Sofiene Ben Ammou, Saad Saguem
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2018-03-01
Serier:BMC Neurology
Fag:
Glutathione-S-transferase M1
Glutathione-S-transferase T1
Epilepsy
Genetic polymorphisms
Carbamazepine
Online adgang:http://link.springer.com/article/10.1186/s12883-018-1013-8
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