Generation of Brain Microvascular Endothelial-like Cells from Human iPS Cell-Derived Endothelial Progenitor Cells Using TGF-β Receptor Inhibitor, Laminin 511 Fragment, and Neuronal Cell Culture Supplements

Brain microvascular endothelial cells (BMECs) constitute the blood–brain barrier (BBB), which prevents the transfer of substances into the brain. Recently, in vitro BBB models using human-induced pluripotent stem (iPS) cell-derived brain microvascular endothelial-like cells (iBMELCs) have been creat...

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Autors principals:	Hiromasa Aoki, Misaki Yamashita, Tadahiro Hashita, Takahiro Iwao, Mineyoshi Aoyama, Tamihide Matsunaga
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2022-12-01
Col·lecció:	Pharmaceutics
Matèries:	human-induced pluripotent stem cell endothelial progenitor cell brain microvascular endothelial cell laminin511 blood–brain barrier transforming growth factor-β receptor inhibitor
Accés en línia:	https://www.mdpi.com/1999-4923/14/12/2697
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