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Full-Term Human Placental Macrophages Eliminate Coxiella burnetii Through an IFN-γ Autocrine Loop

The intracellular bacterium Coxiella burnetii is responsible for Q fever, an infectious disease that increases the risk of abortion, preterm labor, and stillbirth in pregnant women. It has been shown that C. burnetii replicates in BeWo trophoblast cell line and inhibits the activation and maturation...

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Hoofdauteurs: Soraya Mezouar, Imene Benammar, Asma Boumaza, Aïssatou Bailo Diallo, Céline Chartier, Christophe Buffat, John Boudjarane, Philippe Halfon, Maria Katsogiannou, Jean-Louis Mege
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2019-10-01
Reeks:Frontiers in Microbiology
Onderwerpen:
Coxiella burnetii
inflammation
interferon-γ
macrophages
multinuclear giant cells
placenta
Online toegang:https://www.frontiersin.org/article/10.3389/fmicb.2019.02434/full
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