Tripartite motif 47 promotes the development of thyroid carcinoma through ADAR ubiquitination

Abstract Background Tripartite motif 47 (TRIM47) plays a vital role in the carcinogenesis and drug resistance of various cancers, whereas the function of TRIM47 in thyroid carcinoma (TC) remains unclear. Methods Human study and animal experiments were performed. Mass spectrometry, cellular invasion/...

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Main Authors: Hongzhou Liu, Xiaodong Hu, Tan Li, Yuhan Wang, Xiaomin Fu
Formato: Artigo
Idioma:Inglês
Publicado: BMC 2025-07-01
Series:Molecular Medicine
Assuntos:
Thyroid carcinoma
Tripartite motif 47
Adenosine deaminases acting on RNA
Glycogen synthase kinase-3β
Ubiquitination
Phosphorylation
Acceso en liña:https://doi.org/10.1186/s10020-025-01298-z
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