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TRIM21 attenuates renal carcinoma lipogenesis and malignancy by regulating SREBF1 protein stability

Abstract Background Metabolic reprogramming is a hallmark of various cancers. Targeting metabolic processes is a very attractive treatment for cancer. Renal cell carcinoma (RCC) is a type of metabolic disease, and the lipidomic profile of RCC is significantly altered compared with that of healthy ti...

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Hlavní autoři: Xintian Chen, Hongmei Yong, Miaolei Chen, Chuyin Deng, Pengfei Wang, Sufang Chu, Minle Li, Pingfu Hou, Junnian Zheng, Zhongwei Li, Jin Bai
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2023-01-01
Edice:Journal of Experimental & Clinical Cancer Research
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On-line přístup:https://doi.org/10.1186/s13046-022-02583-z
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