YIPF5 is an essential host factor for porcine epidemic diarrhea virus double-membrane vesicle formation

ABSTRACT Porcine epidemic diarrhea virus (PEDV) is a major coronavirus in swine, causing substantial economic losses in the industry. To deepen our understanding of the PEDV–host cell interactions, we performed whole-genome CRISPR/Cas9 screens on porcine IPEC-J2 and IPI-2I cell lines to identify key...

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Detalhes bibliográficos

Principais autores:	Liang Guo, Xiaoyue Duan, Jin Li, Zhuolin Hao, Yuhai Bi, Yuhai Chen, Xuguang Du, Sen Wu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology 2025-06-01
coleção:	Journal of Virology
Assuntos:	porcine epidemic diarrhea virus CRISPR/Cas9 YIPF5 DMVs host factor
Acesso em linha:	https://journals.asm.org/doi/10.1128/jvi.00320-25
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