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Genetic dissection of apoptosis and cell cycle control in response of colorectal cancer treated with preoperative radiochemotherapy

<p>Abstract</p> <p>Background</p> <p>In previous analyses we identified therapy-induced upregulation of the CDK inhibitor p21<sup>CIP/WAF-1 </sup>and consequently decreased tumor cell proliferation or loss of Bax as adverse factors for survival in rectal cancer treated with radiochemotherapy. Here,...

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Bibliografiske detaljer
Principais autores: Hauptmann Steffen, Riess Hanno, Hildebrandt Bert, Wust Peter, Schlag Peter M, Rau Beate, Sturm Isrid, Dörken Bernd, Daniel Peter T
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2006-05-01
Serier:BMC Cancer
Online adgang:http://www.biomedcentral.com/1471-2407/6/124
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