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The Cerebral Brain-Derived Neurotrophic Factor Pathway, Either Neuronal or Endothelial, Is Impaired in Rats with Adjuvant-Induced Arthritis. Connection with Endothelial Dysfunction

Cognitive abilities are largely dependent on activation of cerebral tropomyosin-related kinase B receptors (TrkB) by brain-derived neurotrophic factor (BDNF) that is secreted under a bioactive form by both neurons and endothelial cells. In addition, there is mounting evidence for a link between endo...

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Detalhes bibliográficos
Principais autores: Martin Pedard, Aurore Quirié, Philippe Garnier, Anne Tessier, Céline Demougeot, Christine Marie
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018-01-01
coleção:Frontiers in Physiology
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Acesso em linha:http://journal.frontiersin.org/article/10.3389/fphys.2017.01125/full
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