The inhibition of PGAM5 suppresses seizures in a kainate-induced epilepsy model via mitophagy reduction
BackgroundEpilepsy is a common neurological disease, and excessive mitophagy is considered as one of the major triggers of epilepsy. Mitophagy is a crucial pathway affecting reactive oxygen species. Phosphoglycerate mutase 5 (PGAM5) is a protein phosphatase present in mitochondria that regulates man...
Tallennettuna:
| Päätekijät: | , , , , , , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Frontiers Media S.A.
2022-12-01
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| Sarja: | Frontiers in Molecular Neuroscience |
| Aiheet: | |
| Linkit: | https://www.frontiersin.org/articles/10.3389/fnmol.2022.1047801/full |
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