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Inactivation of DltA modulates virulence factor expression in Streptococcus pyogenes.

D-alanylated lipoteichoic acid is a virtually ubiquitous component of gram-positive cell walls. Mutations in the dltABCD operon of numerous species exhibit pleiotropic effects, including reduced virulence, which has been attributed to increased binding of cationic antimicrobial peptides to the more...

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Detalhes bibliográficos
Principais autores: Kathleen H Cox, Eduardo Ruiz-Bustos, Harry S Courtney, James B Dale, Morgan A Pence, Victor Nizet, Ramy K Aziz, Ivan Gerling, Susan M Price, David L Hasty
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2009-01-01
coleção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC2671602?pdf=render
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