Landscape of T‐cell repertoires with public COVID‐19‐associated T‐cell receptors in pre‐pandemic risk cohorts

Abstract Objectives T cells have an essential role in the antiviral defence. Public T‐cell receptor (TCR) clonotypes are expanded in a substantial proportion of COVID‐19 patients. We set out to exploit their potential use as read‐out for COVID‐19 T‐cell immune responses. Methods We searched for COVI...

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Hlavní autoři:	Donjete Simnica, Christoph Schultheiß, Malte Mohme, Lisa Paschold, Edith Willscher, Antonia Fitzek, Klaus Püschel, Jakob Matschke, Sandra Ciesek, Daniel G Sedding, Yu Zhao, Nicola Gagliani, Yacine Maringer, Juliane S Walz, Janna Heide, Julian Schulze‐zur‐Wiesch, Mascha Binder
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Wiley 2021-01-01
Edice:	Clinical & Translational Immunology
Témata:	COVID‐19 public T‐cell receptors risk cohort T‐cell repertoire
On-line přístup:	https://doi.org/10.1002/cti2.1340
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