Broad-Spectrum HDAC Inhibitors Promote Autophagy through FOXO Transcription Factors in Neuroblastoma

Depending on context and tumor stage, deregulation of autophagy can either suppress tumorigenesis or promote chemoresistance and tumor survival. Histone deacetylases (HDACs) can modulate autophagy; however, the exact mechanisms are not fully understood. Here, we analyze the effects of the broad-spec...

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Autori principali:	Katharina Körholz, Johannes Ridinger, Damir Krunic, Sara Najafi, Xenia F. Gerloff, Karen Frese, Benjamin Meder, Heike Peterziel, Silvia Vega-Rubin-de-Celis, Olaf Witt, Ina Oehme
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2021-04-01
Serie:	Cells
Soggetti:	macroautophagy FOXO1 FOXO3a vorinostat panobinostat neuroblastoma
Accesso online:	https://www.mdpi.com/2073-4409/10/5/1001
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