Antimicrobial Activity of Quasi-Enantiomeric <i>Cinchona</i> Alkaloid Derivatives and Prediction Model Developed by Machine Learning

Bacterial infections that do not respond to current treatments are increasing, thus there is a need for the development of new antibiotics. Series of 20 <i>N</i>-substituted quaternary salts of cinchonidine (CD) and their quasi-enantiomer cinchonine (CN) were prepared and their antimicrobial activit...

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Hlavní autoři:	Alma Ramić, Mirjana Skočibušić, Renata Odžak, Ana Čipak Gašparović, Lidija Milković, Ana Mikelić, Karlo Sović, Ines Primožič, Tomica Hrenar
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2021-05-01
Edice:	Antibiotics
Témata:	quaternary cinchonidines quaternary cinchonines antimicrobial activity cytotoxicity ROS activity/PES model
On-line přístup:	https://www.mdpi.com/2079-6382/10/6/659
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