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Differential microRNA expression in the SH-SY5Y human cell model as potential biomarkers for Huntington’s disease

Huntington’s disease (HD) is caused by an expansion of CAG trinucleotide repeat in the HTT gene; the exact pathogenesis of HD currently remains unclear. One of the promising directions in the study of HDs is to determine the molecular mechanism underlying the development and role of microRNAs (miRNA...

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Principais autores: Ayaz Belkozhayev, Raigul Niyazova, Mohammad Amjad Kamal, Anatoliy Ivashchenko, Kamalidin Sharipov, Cornelia M. Wilson
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2024-07-01
coleção:Frontiers in Cellular Neuroscience
Assuntos:
biomarker
Huntington’s disease
miRNA
nucleotide repeats
target genes
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fncel.2024.1399742/full
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