Evaluating the breast cancer predisposition role of rare variants in genes associated with low-penetrance breast cancer risk SNPs

Abstract Background Genome-wide association studies (GWASs) have identified numerous single-nucleotide polymorphisms (SNPs) associated with small increases in breast cancer risk. Studies to date suggest that some SNPs alter the expression of the associated genes, which potentially mediates risk modi...

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Hlavní autoři:	Na Li, Simone M. Rowley, Ella R. Thompson, Simone McInerny, Lisa Devereux, Kaushalya C. Amarasinghe, Magnus Zethoven, Richard Lupat, David Goode, Jason Li, Alison H. Trainer, Kylie L. Gorringe, Paul A. James, Ian G. Campbell
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2018-01-01
Edice:	Breast Cancer Research
Témata:	Familial breast cancer Single-nucleotide polymorphism (SNP) Predisposition genes Breast cancer susceptibility
On-line přístup:	http://link.springer.com/article/10.1186/s13058-017-0929-z
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