Simple adjustment of the sequence weight algorithm remarkably enhances PSI-BLAST performance
Abstract Background PSI-BLAST, an extremely popular tool for sequence similarity search, features the utilization of Position-Specific Scoring Matrix (PSSM) constructed from a multiple sequence alignment (MSA). PSSM allows the detection of more distant homologs than a general amino acid substitution...
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| Principais autores: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BMC
2017-06-01
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| Serier: | BMC Bioinformatics |
| Fag: | |
| Online adgang: | http://link.springer.com/article/10.1186/s12859-017-1686-9 |
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