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The clinical relevance of heme detoxification by the macrophage heme oxygenase system

Heme degradation by the heme oxygenase (HMOX) family of enzymes is critical for maintaining homeostasis and limiting heme-induced tissue damage. Macrophages express HMOX1 and 2 and are critical sites of heme degradation in healthy and diseased states. Here we review the functions of the macrophage h...

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Principais autores: Scott Yeudall, Clint M. Upchurch, Norbert Leitinger
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Immunology
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Acceso en liña:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1379967/full
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