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A Novel Toxin from Haplopelma lividum Selectively Inhibits the NaV1.8 Channel and Possesses Potent Analgesic Efficacy

Spider venoms are a complex mixture of peptides with a large number of neurotoxins targeting ion channels. Although thousands of peptide toxins have been identified from venoms of numerous species of spiders, many unknown species urgently need to be investigated. In this study, a novel sodium channe...

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Autori principali: Ping Meng, Honggang Huang, Gan Wang, Shilong Yang, Qiuming Lu, Jingze Liu, Ren Lai, Mingqiang Rong
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2016-12-01
Serie:Toxins
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Accesso online:http://www.mdpi.com/2072-6651/9/1/7
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