The role of AGEs in pathogenesis of cartilage destruction in osteoarthritis

Osteoarthritis (OA) is a degenerative disease resulting from progressive joint destruction caused by many factors. Its pathogenesis is complex and has not been elucidated to date. Advanced glycation end products (AGEs) are a series of irreversible and stable macromolecular complexes formed by reduci...

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Autori principali:	Chao-Peng He, Cheng Chen, Xin-Chen Jiang, Hui Li, Li-Xin Zhu, Ping-Xiao Wang, Tao Xiao
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	The British Editorial Society of Bone & Joint Surgery 2022-05-01
Serie:	Bone & Joint Research
Soggetti:	osteoarthritis advanced glycation end products cartilage extracellular matrix chondrocyte apoptosis chondrocyte autophagy osteoarthritis (oa) pathogenesis cartilage destruction chondrocytes apoptosis autophagy degenerative diseases extracellular matrix (ecm) degradation progressive joint destruction lipid
Accesso online:	https://online.boneandjoint.org.uk/doi/epdf/10.1302/2046-3758.115.BJR-2021-0334.R1
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