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Hormone-sensitive lipase drives pro-resolving macrophage polarization and enhances efferocytosis

Abstract Background Lipid droplets (LDs) are vital organelles in cellular energy regulation, controlling lipid storage and mobilization. However, their specific roles in macrophage function, particularly in the context of immune regulation, remain elusive. This study aimed to elucidate how LD manipu...

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Hauptverfasser: Haruki Watanabe, Brianna Palacio, Moses Lee, Hei Sook Sul, Junhwan Kim, Betty Diamond, Myoungsun Son
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2026-01-01
Schriftenreihe:Cell Communication and Signaling
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Online-Zugang:https://doi.org/10.1186/s12964-025-02631-z
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