Short-course aminoglycosides as adjunctive treatment in adults with sepsis: A post-hoc analysis of a prematurely terminated cluster randomized trial

Background: Cephalosporin monotherapy or cephalosporin-aminoglycoside combination therapy are both used for empirical sepsis treatment in The Netherlands, with no evidence favouring either. We hypothesized that ceftriaxone or cefuroxime monotherapy is non-inferior to cefuroxime combined with gentami...

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Bibliografski detalji

Glavni autori:	Eva L. Koekenbier, Sharon E.J.D. van den Eijnde, Paul D. van der Linden, Jan Jelrik Oosterheert, Elske Sieswerda, Lisanne E.M. Vintcent, Linda M. Kampschreur, Hjalmar R. Bouma, Heidi S.M. Ammerlaan, Michelle Gompelman, Eefje Jong, Jan M. Prins, Anton S.M. Dofferhoff, Marc J.M. Bonten, Cornelis H. van Werkhoven
Format:	Artigo
Jezik:	Inglês
Izdano:	Elsevier 2025-06-01
Serija:	CMI Communications
Teme:	Cephalosporin Aminoglycosides Combination therapy Community-aquired sepsis Sepsis Cluster-randomized
Online pristup:	http://www.sciencedirect.com/science/article/pii/S2950590925000174
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