Monitoring of Early Changes of Circulating Tumor DNA in the Plasma of Rectal Cancer Patients Receiving Neoadjuvant Concomitant Chemoradiotherapy: Evaluation for Prognosis and Prediction of Therapeutic Response

Introduction: Patients with locally advanced rectal cancer (LARC) are undergoing neoadjuvant chemoradiotherapy (NCRT) prior to surgery. Although in some patients the NCRT is known to prevent local recurrence, it is also accompanied by side effects. Accordingly, there is an unmet need to identify pre...

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Principais autores:	Filip Pazdirek, Marek Minarik, Lucie Benesova, Tereza Halkova, Barbora Belsanova, Milan Macek, Lubomír Stepanek, Jiri Hoch
Formato:	Artigo
Idioma:	Inglês
Publicado:	Frontiers Media S.A. 2020-07-01
Series:	Frontiers in Oncology
Assuntos:	rectal cancer neoadjuvant chemoradiotherapy circulating tumor ctDNA prediction prognosis response
Acceso en liña:	https://www.frontiersin.org/article/10.3389/fonc.2020.01028/full
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