Mucosal administration of a live attenuated recombinant COVID-19 vaccine protects nonhuman primates from SARS-CoV-2

Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of the COVID-19 global pandemic. SARS-CoV-2 is an enveloped RNA virus that relies on its trimeric surface glycoprotein spike for entry into host cells. Here we describe the COVID-19 vaccine candidate MV-014-...

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Autori principali:	Mariana F. Tioni, Robert Jordan, Angie Silva Pena, Aditya Garg, Danlu Wu, Shannon I. Phan, Christopher M. Weiss, Xing Cheng, Jack Greenhouse, Tatyana Orekov, Daniel Valentin, Swagata Kar, Laurent Pessaint, Hanne Andersen, Christopher C. Stobart, Melissa H. Bloodworth, R. Stokes Peebles, Yang Liu, Xuping Xie, Pei-Yong Shi, Martin L. Moore, Roderick S. Tang
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Portfolio 2022-07-01
Serie:	npj Vaccines
Accesso online:	https://doi.org/10.1038/s41541-022-00509-6
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