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Binimetinib (MEK162) in recurrent low-grade serous ovarian cancer resistant to chemotherapy and hormonal treatment

Background: Management of advanced/recurrent low-grade serous ovarian carcinoma (LGOSC) is often challenging. Effective treatment options remain limited for hormone and chemotherapy-resistant LGSOC.CASE: A 65-year-old woman with recurrent widespread LGSOC harboring the KRAS-G12 V hotspot mutation ex...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Chanhee Han, Stefania Bellone, Luca Zammataro, Peter E. Schwartz, Alessandro D. Santin
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Elsevier 2018-08-01
Rangatū:Gynecologic Oncology Reports
Urunga tuihono:http://www.sciencedirect.com/science/article/pii/S235257891830047X
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