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Bioinformatics analysis and experimental verification of the cancer-promoting effect of DHODH in clear cell renal cell carcinoma

Abstract Clear cell renal cell carcinoma (ccRCC) is a malignant tumor of the urinary system. To explore the potential mechanisms of DHODH in ccRCC, we analyzed its molecular characteristics using public databases. TCGA pan-cancer dataset was used to analyze DHODH expression in different cancer types...

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Gardado en:
Principais autores: Songsong Wang, Yan Li, Yilong Lin, Junting Li, Lang Guo, Haoyu Wang, Xinyuan Lin, Ziming Liu, Bingqi Zhang, Zhengming Liao, Zhongmin Zhang
Formato: Artigo
Idioma:Inglês
Publicado: Nature Portfolio 2024-05-01
Series:Scientific Reports
Assuntos:
Apoptosis
Bioinformatics
Clear cell renal cell carcinoma
DHODH
Ferroptosis
Immunotherapy
Acceso en liña:https://doi.org/10.1038/s41598-024-62738-0
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