An expanded population of CD8dim T cells with features of mitochondrial dysfunction and senescence is associated with persistent HIV-associated Kaposi’s sarcoma under ART

HIV-associated Kaposi’s sarcoma (KS), which is caused by Kaposi’s sarcoma-associated herpesvirus, usually arises in the context of uncontrolled HIV replication and immunosuppression. However, disease occasionally occurs in individuals with durable HIV viral suppression and CD4 T cell recovery under...

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Автори:	Genevieve T. Clutton, Ann Marie K. Weideman, Nilu P. Goonetilleke, Toby Maurer
Формат:	Artigo
Мова:	Inglês
Опубліковано:	Frontiers Media S.A. 2022-09-01
Серія:	Frontiers in Cell and Developmental Biology
Предмети:	Kaposi’s sarcoma KSHV HIV T cells CD8 coreceptor metabolism
Онлайн доступ:	https://www.frontiersin.org/articles/10.3389/fcell.2022.961021/full
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